4.7 Article

Multifunctional isoquinoline-oxazoline ligands of chemical and biological importance

期刊

CHEMICAL COMMUNICATIONS
卷 55, 期 42, 页码 5902-5905

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc01790a

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资金

  1. National Key R&D Program of China [2018YFD0201000]
  2. National Natural Science Foundation of China [21772094]
  3. Fundamental Research Funds for the Central Universities [KYZ201706]

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Multifunctional isoquinoline- oxazolines ( MIQOXs) were conceived and synthesized from commercially available chiral amino acids. The multifunctional role of MIQOXs was demonstrated by Pdcatalyzed highly enantioselective addition of arylboronic acids to nitrostyrenes, and by the discovery of novel antifungal candidates.

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