Immobilization of amidase into a magnetic hierarchically porous metal-organic framework for efficient biocatalysis

A novel magnetic hierarchically porous metal-organic framework (MOF) has been successfully fabricated via a modulator-induced defectformation strategy. Amidase for the first time has been immobilized into this magnetic carrier and the resultant bio-composite exhibits superior enzymatic catalysis performance compared to the free enzyme and its counterparts without hierarchical porosity.