期刊
ECHOCARDIOGRAPHY-A JOURNAL OF CARDIOVASCULAR ULTRASOUND AND ALLIED TECHNIQUES
卷 32, 期 8, 页码 1222-1227出版社
WILEY
DOI: 10.1111/echo.12926
关键词
tricuspid annular plane systolic excursion; right ventricular systolic dysfunction; critically ill patients; length of stay
资金
- Innovative grant program through the Albert Einstein Society (AES)
BackgroundTransient left ventricular dysfunction can occur under conditions of extreme emotional or physiological stress. There is little data on right ventricular function in such situations. MethodsOne hundred twenty patients admitted to an ICU with a noncardiac illness were studied. Those with documented coronary disease, ejection fraction <40%, sepsis, or intracranial hemorrhage were excluded. Echocardiograms were performed within 24hours of admission. Tricuspid annular plane systolic excursion (TAPSE) was measured to assess right ventricular systolic function. Plasma catecholamines (norepinephrine, epinephrine, dopamine) were measured on admission. Clinical and demographic data were collected, along with data on ICU length of stay (LOS), hospital LOS, and in-hospital and long-term mortality. TAPSE was tested for correlation with adverse outcomes and length of stay. ResultsMean TAPSE for the group was 2.050.66cm. Based on area under the ROC curve analysis, TAPSE <2.4cm was the best cutoff for predicting in-hospital and long-term mortality. There were 13 in-hospital deaths, 12 in the group with TAPSE <2.4cm and one among those with TAPSE 2.4cm. On multivariate analysis, TAPSE <2.4cm was a significant predictor of in-hospital mortality ((2)=4.6, P=0.03). When tested against hospital LOS, an inverse correlation was found (P=0.04). No association was found between TAPSE and catecholamine levels. ConclusionsRight ventricular systolic function, as assessed by TAPSE, has important prognostic value in critically ill patients. Mean values were lower in patients who died in-hospital versus those who survived to discharge. In addition, patients with TAPSE <2.4cm had a longer hospital length of stay.
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