期刊
CHEMICAL COMMUNICATIONS
卷 55, 期 28, 页码 4051-4054出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc00603f
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资金
- National Natural Science Foundation of China [11875269, 21574136, 11375213]
- CAS Youth Innovation Promotion Association Program [2015008]
- Hundred Talents Program of CAS
Mitochondria emerge as an important target for cancer therapy. Herein, by taking advantage of the recently reported high temperature of mitochondria, a well-tuned thermoresponsive nanocarrier was developed for specifically delivering the anticancer drug, paclitaxel (PTX), to mitochondria in cancer cells. The temperature-dependent delivery of drugs to mitochondria represents a novel anticancer strategy.
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