期刊
CHEMICAL COMMUNICATIONS
卷 55, 期 29, 页码 4194-4197出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc00256a
关键词
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Natural-product macrolide 10,11-dehydrocurvularin (DCV) was revealed to be a potent irreversible inhibitor of ATP-citrate lyase (ACLY) via classical chemoproteomic profiling, which mechanistically illuminates the anti-cancer mode of action of DCV and its analogues.
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