期刊
THERANOSTICS
卷 9, 期 14, 页码 4030-4046出版社
IVYSPRING INT PUBL
DOI: 10.7150/thno.33112
关键词
lymphocytes; immune response; heart diseases
资金
- National Natural Science Foundation of China [81722008, 91639101, 81570362]
- Innovation Program of Shanghai Municipal Education Commission [2017-01-07-00-09-E00042]
- Science and Technology Commission of Shanghai Municipality [17010500100, 18410722200]
- Sailing Program from Science and Technology Commission of Shanghai [19YF1415400]
- Horizon2020 ERC-2016-COG EVICARE [725229]
- Technobeat [668724]
- development fund for Shanghai talents
Heart diseases are one of the leading causes of death for humans in the world. Increasing evidence has shown that myocardial injury induced innate and adaptive immune responses upon early cellular damage but also during chronic phases post-injury. The immune cells can not only aggravate the injury but also play an essential role in the induction of wound healing responses, which means they play a complex role throughout the acute inflammatory response and reparative response after cardiac injury. This review will summarize the current experimental and clinical evidence of lymphocytes, one of the major types of immune cells, participate in heart diseases and try to explain the possible role of these immune cells following cardiac injury.
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