期刊
GENERAL PHYSIOLOGY AND BIOPHYSICS
卷 38, 期 2, 页码 187-190出版社
GENERAL PHYSIOL AND BIOPHYSICS
DOI: 10.4149/gpb_2019003
关键词
Post-traumatic stress disorder; Predator scent stress; Serotonin; Norepinephrine; Dopamine; HPLC
资金
- Russian Science Foundation [17-15-01318]
- Russian Science Foundation [17-15-01318] Funding Source: Russian Science Foundation
The aim of this study was to investigate the effect of chronic predator scent stress (PSS) on monoamine levels in rat thalamus and hypothalamus. Rats were exposed to the PSS (sand containing cat urine) for ten minutes daily for ten days. Control animals were exposed to the sand containing clean water. Fifteen days later, rats' behavior and thalamic and hypothalamic levels of monoamines were analyzed. PSS rats had elevated anxiety, increased thalamic serotonin and decreased hypothalamic dopamine concentrations. This decrease in hypothalamic dopamine may explain, at least in part, lowered corticosterone levels observed in PSS animals in our previous studies.
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