期刊
JOURNAL OF THE ENDOCRINE SOCIETY
卷 3, 期 6, 页码 1150-1153出版社
ENDOCRINE SOC
DOI: 10.1210/js.2019-00046
关键词
cortisol; modified-release; adrenal insufficiency; outcomes
资金
- Shire Pharmaceuticals
The appreciation of the unacceptable outcomes of patients with adrenal insufficiency has brought new developments in glucocorticoid replacement therapy. Efforts have moved beyond simple dose adjustments of the traditional immediate-release hydrocortisone to new formulations of hydrocortisone aimed at mimicking the circadian pattern of physiological glucocorticoid release. The present report has briefly summarized the evidence base behind recent studies that have reported benefits using modified-release preparations and set this in context for today's clinical practice. Copyright (C) 2019 Endocrine Society
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