期刊
CHEMICAL COMMUNICATIONS
卷 55, 期 50, 页码 7235-7238出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc02186h
关键词
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An NMR approach based on parahydrogen hyperpolarization is presented to detect and resolve specific classes of metabolites in complex biomixtures at down to nanomolar concentrations. We demonstrate our method on solid phase extracts of urine, by simultaneously observing hundreds of metabolites well below the limits of detection of thermal NMR.
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