期刊
JOURNAL OF THORACIC AND CARDIOVASCULAR SURGERY
卷 153, 期 1, 页码 21-+出版社
MOSBY-ELSEVIER
DOI: 10.1016/j.jtcvs.2016.07.080
关键词
aortic valve replacement; trifecta; durability; outcomes
Objective: To clarify the mid-term durability of the Trifecta bioprosthesis for aortic valve replacement (AVR). Methods: We retrospectively analyzed the prospectively collected data of 824 consecutive implants of the Trifecta valve at a single institution. A 100% complete follow-up was available (average duration, 2.2 +/- 1.3 years; range, 0.03-6.9 years; 1747.6 patient-years). Echocardiography data at discharge were recorded prospectively. Results: Operative mortality was 3.8%; 2.7% in patients receiving isolated AVR. There were 5 valve-related early reoperations, including 1 for infective prosthetic endocarditis and 4 for nonstructural valve dysfunction. The global rate of severe patient-prosthesis mismatch was 1.26%. Overall 5-year survival was 74.9%, and freedom from valve-related death was 97.8%. The majority of deaths attributed to the valve were due to unknown causes. We observed 6 SVD events at 3.4 +/- 1.6 years after surgery. At 5 years, the actuarial freedom from SVD was 98% +/- 0.9% (n = 6), freedom from reintervention for SVD was 98% +/- 0.9% (n +/- 5, including 2 transcatheter valve-in-valve), and freedom from open reoperation for SVD was 98.9% +/- 0.6%. The 5-year freedom from prosthetic endocarditis was 97.7% +/- 0.7% (n = 12, 6 requiring reoperation). There was 1 case of late NSVD (5-year freedom, 99.8% +/- 0.2%). Freedom from hemorrhagic events was 98.6% +/- 0.5%(86% occurring in patients on anticoagulants); there were no thromboembolic events at follow-up. Conclusions: The Trifecta bioprosthesis is a reliable device for AVR. We confirm excellent immediate hemodynamic properties and a very low rate of patient-prosthesis mismatch. The absolute number of SVD cases observed remains limited; nevertheless, their timing, pathological characteristics, and clinical presentation mandate continued follow-up.
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