期刊
ORGANIC & BIOMOLECULAR CHEMISTRY
卷 17, 期 25, 页码 6148-6152出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9ob01156k
关键词
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资金
- Shandong Provincial Natural Science Foundation, China [ZR2016JL009]
- University of Jinan
An acetic acid-promoted approach that enables the synthesis of 1,4,5-trisubstituted 1,2,3-triazole derivatives has been achieved. This transformation employs readily available primary amines, 1,3-dicarbonyls and tosyl azide as the starting materials via a cycloaddition reaction under metal-free conditions. The reaction provides a simple access to fully substituted 1,2,3-triazoles from commercial substrates in moderate to excellent yields.
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