Comparative efficacy of Bentonite clay, activated charcoal and Trichosporon mycotoxinivorans in regulating the feed-to-tissue transfer of mycotoxins

BACKGROUNDMycotoxins contamination in animal products and by-products is a persistent threat to the food and feed industry. The present study was designed to evaluate the comparative inhibitory effects of Bentonite (BN), activated charcoal (AC) and a newly discovered yeast, Trichosporon mycotoxinivorans (TM), against feed-to-tissue transfer of mycotoxins. RESULTSA dose dependent increase as determined by HPLC, in the residues of aflatoxin B1 (AFB1) and ochratoxin A (OTA) was exhibited in the groups of birds fed AFB1 and OTA alone. The dietary addition of BN and AC to AFB1-contaminated diets resulted in a 41-87% and 16-72% decrease in AFB1 residues in liver of the birds, respectively. However, this decrease was non-significant with addition of TM as AFB1 binder. A partial to non-significant protection was observed by dietary BN and AC, against OTA residues, while a significant decrease in OTA residues (38-84%) was noted in TM-OTA co-fed groups. CONCLUSIONThe order of efficacy in terms of lowering AFB1 residues in the liver was BN>AC>TM, while against OTA it was TM>BN>AC. The findings of present study suggest that, based upon the nature of target mycotoxins, a mixture of multi-mycotoxins binders/detoxifiers should be incorporated in the animal feeds. (c) 2017 Society of Chemical Industry