4.3 Article

Active Materials Integrated with Actomyosin

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PHYSICAL SOC JAPAN
DOI: 10.7566/JPSJ.86.101001

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  1. JSPS KAKENHI [JP25103012, JP26707020, JP17J06827]
  2. Grants-in-Aid for Scientific Research [25103001, 26707020, 17J06827, 16H06933] Funding Source: KAKEN

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Muscles are the engine of our body, and actomyosin is the engine of a cell. Both muscle and the actomyosin use the same proteins, namely, actin, and myosin, which are the pair of cytoskeleton and motor proteins generating a force to realize deformation. The properties of force generation by actomyosin at a single-molecule level have been studied for many years. Moreover, the active properties of higher-order structures integrated by actomyosin are attracting the attention of researchers. Here, we review the recent progress in the study of reconstituted actomyosin systems in vitro toward real-space models of nonequilibrium systems, collective motion, biological phenomena, and active materials.

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