期刊
NEURAL REGENERATION RESEARCH
卷 14, 期 8, 页码 1343-1351出版社
WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/1673-5374.253511
关键词
nerve regeneration; peripheral nerve injury; nerve conduits; decellularization; extracellular matrix; Schwann cell; neural regeneration
资金
- National Key R & D Program of China [2017YFA0104701]
- National Natural Science Foundation of China [31771052]
- Natural Science Foundation of Beijing of China [7172202]
- PLA Youth Training Project for Medical Science of China [16QNP144]
In recent years, the use of Schwann cell transplantation to repair peripheral nerve injury has attracted much attention. Animal-based studies show that the transplantation of Schwann cells in combination with nerve scaffolds promotes the repair of injured peripheral nerves. Autologous Schwann cell transplantation in humans has been reported recently. This article reviews current methods for removing the extracellular matrix and analyzes its composition and function. The development and secretory products of Schwann cells are also reviewed. The methods for the repair of peripheral nerve injuries that use myelin and Schwann cell transplantation are assessed. This survey of the literature data shows that using a decellularized nerve conduit combined with Schwann cells represents an effective strategy for the treatment of peripheral nerve injury. This analysis provides a comprehensive basis on which to make clinical decisions for the repair of peripheral nerve injury.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据