3.9 Article

Clinic and ambulatory blood pressure in a population-based sample of African Americans: the Jackson Heart Study

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ELSEVIER SCIENCE INC
DOI: 10.1016/j.jash.2017.02.001

关键词

Ambulatory blood pressure monitoring; masked hypertension; nocturnal hypertension; nondipping

资金

  1. National Heart, Lung, and Blood Institute [R01 HL117323, K24-HL125704, HHSN268201300046C, HSN268201300047C, HHSN 268201300048C, HHSN268201300049C, HHSN268201300050C]
  2. American Heart Association [15SFRN2390002]
  3. National Institute on Minority Health and Health Disparities

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Blood pressure (BP) can differ substantially when measured in the clinic versus outside of the clinic setting. Few population based studies with ambulatory blood pressure monitoring (ABPM) include African Americans. We calculated the prevalence of clinic hypertension and ABPM phenotypes among 1016 participants in the population-based Jackson Heart Study, an exclusively African-American cohort. Mean daytime systolic BP was higher than mean clinic systolic BP among participants not taking antihypertensive medication (127.1[standard deviation 12.8] vs. 124.5[15.7] mm Hg, respectively) and taking anti hypertensive medication (131.2[13.6] vs. 130.0[15.6] mm Hg, respectively). Mean daytime diastolic BP was higher than clinic diastolic BP among participants not taking antihypertensive medication (78.2[standard deviation 8.9] vs. 74.6[8.4] mm Hg, respectively) and taking antihypertensive medication (77.6[9.4] vs. 74.3[8.5] mm Hg, respectively). The prevalence of daytime hypertension was higher than clinic hypertension for participants not taking antihypertensive medication (31.8% vs. 14.3%) and taking antihypertensive medication (43.0% vs. 23.1%). A high percentage of participants not taking and taking antihypertensive medication had nocturnal hypertension (49.4% and 61.7%, respectively), white-coat hypertension (30.2% and 29.3%, respectively), masked hypertension (25.4% and 34.6%, respectively), and a nondipping BP pattern (62.4% and 69.6%, respectively). In conclusion, these data suggest hypertension may be misdiagnosed among African Americans without using ABPM. (C) 2017 American Society of Hypertension. All rights reserved.

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