期刊
JOURNAL OF THE AMERICAN MEDICAL DIRECTORS ASSOCIATION
卷 18, 期 5, 页码 -出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jamda.2017.01.024
关键词
Pain; dementia; analgesics; quality of life; mortality; depression
资金
- National Institute for Health Research Collaboration for Leadership in Applied Health Research and Care SouthWest Peninsula
- National Institute for Health Research [CL-2015-17-008, RP-PG-0608-10133] Funding Source: researchfish
Introduction: Knowledge regarding the longitudinal course, impact, or treatment implications of pain in people with dementia living in care homes is very limited. Methods: We investigated the people with dementia living in 67 care homes in London and Buckinghamshire, United Kingdom. Pain, dementia severity, neuropsychiatric symptoms, depression, agitation, and quality-of-life were measured using appropriate instruments at baseline (N = 967) and after 9 months (n = 629). Results: Baseline prevalence of pain was 35.3% (95% CI 32.3-38.3). Pain severity was significantly correlated with dementia severity, neuropsychiatric symptoms, depression, agitation, and quality of life at both time points. Regular treatment with analgesics significantly reduced pain severity. Pain was significantly associated with more antipsychotic prescriptions. Pain was significantly associated (OR 1.48; 95% CI 1.18-1.85) with all-cause mortality during follow-up. Conclusions: Pain is an important determinant of neuropsychiatric symptoms, mortality, quality-of-life, and antipsychotic prescriptions. Improved identification, monitoring, and treatment of pain are urgent priorities to improve the health and quality-of-life for people with dementia. (C) 2017 AMDA -The Society for Post-Acute and Long-Term Care Medicine.
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