期刊
ANTIOXIDANTS
卷 8, 期 6, 页码 -出版社
MDPI
DOI: 10.3390/antiox8060174
关键词
tyrosol; homovanillyl alcohol; hydroxytyrosol; dimethyl carbonate; lipophilic alkyl esters; hydroxytyrosol-enriched extracts; Olea europaea; green chemistry; circular economy
资金
- MIUR (Ministry for Education, University and Research) [232/216]
Low-molecular weight phenols such as tyrosol, homovanillyl alcohol and hydroxytyrosol are valuable compounds that exhibit a high number of health-promoting effects such as antioxidant, anti-inflammatory and anticancer activity. Despite these remarkable properties, their applications such as dietary supplements and stabilizers of foods and cosmetics in non-aqueous media are limited for the hydrophilic character. With the aim to overcome this limitation, the paper describes a simple and low-cost procedure for the synthesis of lipophilic esters of tyrosol, homovanillyl alcohol and hydroxytyrosol. The reactions were carried out under mild and green chemistry conditions, at room temperature, solubilizing the phenolic compounds in dimethyl carbonate, an eco-friendly solvent, and adding a little excess of the appropriate C2-C18 acyl chloride. The final products were isolated in good yields. Finally, according to the circular economy strategy, the procedure was applied to hydroxytyrosol-enriched extracts obtained by Olea europaea by-products to prepare a panel of lipophilic extracts that are useful for applications where solubility in lipid media is required.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据