4.8 Article

Oxidative 1,2-Difunctionalization of Ethylene via Gold-Catalyzed Oxyarylation

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JOURNAL OF THE AMERICAN CHEMICAL SOCIETY
卷 139, 期 36, 页码 12386-12389

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AMER CHEMICAL SOC
DOI: 10.1021/jacs.7b06668

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资金

  1. EPSRC [EP/G036764/1]
  2. Syngenta
  3. Royal Society
  4. Engineering and Physical Sciences Research Council [EP/K03927X/1, EP/L011999/1, 1515996] Funding Source: researchfish
  5. EPSRC [EP/L011999/1, EP/K03927X/1] Funding Source: UKRI

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Under the conditions of oxidative gold catalysis, exposure of ethylene to aryl silanes and alcohols generates products of 1,2-oxyarylation. This provides a rare example of a process that allows catalytic differential 1,2-difunctionalization of this feedstock chemical.

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