4.7 Article

A new mitochondrion targetable fluorescent probe for carbon monoxide-specific detection and live cell imaging

期刊

CHEMICAL COMMUNICATIONS
卷 55, 期 64, 页码 9444-9447

出版社

ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc03909k

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资金

  1. NSFC [21705120, 81774125]
  2. Natural Science Foundation of Shandong Province, China [ZR2017LB016]
  3. Project of Shandong Province Higher Educational Science and Technology Program & Medical and Health Technology Development [J17KB074, 2017WS241]
  4. Chinese Medicine Science and Technology Development Project of Shandong Province [2017-208]
  5. Open Research Fund of Beijing National Laboratory for Molecular Sciences [BNLMS201812]
  6. Technology Research Project of Weifang [2017GX091]

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A new mitochondrion targetable molecular probe for carbon monoxide (CO)-specific detection based on palladium-free mediated opening of spirolactam was designed. The turn-on red fluorescence caused by CO enables a safe and powerful method for unravelling the function of CO in biological systems to be established.

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