Multicomponent synthesis of pyrano[2,3-d]pyrimidine derivatives via a direct one-pot strategy executed by novel designed copperated Fe3O4@polyvinyl alcohol magnetic nanoparticles

Recently, attention to magnetic nanoparticles has been increased because of their extreme active surface area, composition, and magnetic separation capability. In this regard, a magnetic nanocatalyst system was designed and used for facilitating one-pot synthesis of pyrano[2,3-d]pyrimidine derivatives. This product takes advantages of copper(II) ions chelated with oxygen atoms of polyvinyl alcohol (PVA) strands, which were well composited with iron oxide magnetic nanoparticles during an in situ process. High reaction yields were obtained by using this efficient nanocatalyst in the short times and under mild conditions. High hydrophilicity, convenient separation, and acceptable recyclability have been investigated and introduced as the features of this nanocatalyst. Structural studies related to the nanoscale materials have also been carried out and well interpreted in this report. (C) 2019 Elsevier Ltd. All rights reserved.