期刊
JOURNAL OF SURGICAL ONCOLOGY
卷 117, 期 6, 页码 1267-1277出版社
WILEY
DOI: 10.1002/jso.24945
关键词
biliary drainage; endoscopic biliary drainage; hilar cholangiocarcinoma; outcomes; percutaneous transhepatic biliary drainage
资金
- China Scholarship Council
Background and ObjectivesThe objective of the current study was to define long-term survival of patients with resectable hilar cholangiocarcinoma (HCCA) after preoperative percutaneous transhepatic biliary drainage (PTBD) versus endoscopic biliary drainage (EBD). MethodsBetween 2000 and 2014, 240 patients who underwent curative-intent resection for HCCA were identified at 10 major hepatobiliary centers. Postoperative morbidity and mortality, as well as disease-specific survival (DSS) and recurrence-free survival (RFS) were analyzed among patients. ResultsThe median decrease in total bilirubin levels after biliary drainage was similar comparing PTBD (n=104) versus EBD (n=92) (mg/dL, 4.9 vs 4.9, P=0.589) before surgery. There was no difference in baseline demographic characteristics, type of surgical procedure performed, final AJCC tumor stage or postoperative morbidity among patients who underwent EBD only versus PTBD (all P>0.05). Patients who underwent PTBD versus EBD had a comparable long-term DSS (median, 43.7 vs 36.9 months, P=0.802) and RFS (median, 26.7 vs 24.0 months, P=0.571). The overall pattern of recurrence relative to regional or distant disease was also the same among patients undergoing PTBD and EBD (P=0.669) ConclusionsOncologic outcomes including DSS and RFS were similar among patients who underwent PTBD versus EBD with no difference in tumor recurrence location.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据