4.6 Article

Silver-mediated radical phosphorylation/cyclization of N-allylbenzamides to access phosphoryl-substituted dihydroisoquinolones

期刊

NEW JOURNAL OF CHEMISTRY
卷 43, 期 31, 页码 12221-12224

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ROYAL SOC CHEMISTRY
DOI: 10.1039/c9nj02833a

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资金

  1. NSFC [21501010]
  2. China Postdoctoral Science Foundation [2019M652561]
  3. Key Research Projects of Universities in Henan Province [19A350011]
  4. Hunan Provincial Key Laboratory of Materials Protection for Electric Power and Transportation [2019CL03]

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A silver-mediated phosphorylation/cyclization of N-allylbenzamides with phosphine oxides for the synthesis of phosphoryl-substituted dihydroisoquinolones was developed. This protocol features broad substrate scope, experimental simplicity, high efficiency, step-economy, and facile scalability.

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