期刊
ENDOSCOPIC ULTRASOUND
卷 8, 期 4, 页码 261-268出版社
WOLTERS KLUWER MEDKNOW PUBLICATIONS
DOI: 10.4103/eus.eus_14_19
关键词
Cancer; EUS; fine-needle biopsy; pancreas; ProCore needle
Background and Objective: EUS-guided fine-needle biopsy has become the standard for tissue sampling. A new 20G ProCore (TM) (PC) needle has been developed to overcome the limitations of tissue acquisition of the smaller needles (22G. 25G) and the rigidity of the larger one (19G). The aim of this study is to assess the performance of the 20G PC needle. Materials and Methods: Patients who underwent EUS-guided tissue acquisition with the 20G PC needle of pancreatic and extra-pancreatic mass lesions were retrospectively identified at three Italian centers (Bologna, Fermo, and Palermo). Diagnostic adequacy, accuracy, and tissue core acquisition were the outcome measures. All the cases were performed without rapid on-site evaluation. Results: A total of 384 patients with pancreatic (62.2%) and extra-pancreatic lesions were included in the study. For pancreatic lesions, adequacy, accuracy, sensitivity, and specificity were 92.4%, 91.5%, 90.8% and 100%, respectively, with a number needed to misdiagnose (NNM) of 11.8. The tissue core was obtained in 72% of cases. Transduodenal approach was performed in 150 pancreatic lesions; adequacy, accuracy, and tissue core acquisition were 88.7% 90%, and 66% respectively (NNM 10). For extrapancreatic lesions. adequacy, accuracy, sensitivity, specificity, and tissue core sampling were 95.3%, 95.3%, 92.6%, 100%, and 84.5% (NNM 21.3). Conclusions: The 20G PC needle showed high diagnostic adequacy and accuracy, regardless the access route.
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