Prevalence and Genetic Characterization of Porcine Circovirus Type 3 in Guangxi Province from 2009 to 2017

Porcine circovirus 3 (PCV3) is a novel porcine circovirus type recently reported in many countries. PCV3 has suspected links to porcine dermatitis and nephropathy syndrome (PDNS). In this study, 843 tissue and serum samples of pigs collected between 2009 and 2017 in Guangxi province of China were tested for PCV3. The tissue and serum positive rate of PCV3 was 7.44 and 2.96%, respectively. PCV3 could be detected from different tissues of pigs showed that it has wide tissue tropism. Fifteen complete genome sequences of PCV3 were obtained and showed high genetic identity with other PCV3 isolates. A recombinant cluster had been found based on the phylogenetic tree analyses and similarity plot analyses of ORF2. Our study identified PCV3 was found widely spread in the Guangxi region since 2009. Genomic recombination in different clusters of PCV3 indicated the possible genetic and molecular evolution in the virus. (C) 2018 PVJ. All rights reserved