A zirconium-based metal-organic framework sensitized by thioflavin-T for sensitive photoelectrochemical detection of C-reactive protein

Herein, a novel photoelectrochemical (PEC) assay was developed for the sensitive detection of C-reactive protein (CRP) based on a zirconium-based metal-organic framework (PCN-777) as the photoelectric material and thioflavin-T (Th-T) as the effective signal sensitizer coupled with rolling circle amplification (RCA).