期刊
ANALYST
卷 144, 期 18, 页码 5497-5503出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9an01103j
关键词
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资金
- Open Research Fund Program of the State Key Laboratory of Virology of China [2018KF003]
- China Postdoctoral Science Foundation [2018M643535]
p-Nitrophenol (p-NP) pollutants are widely present in soil and aquatic environments and can seriously impair the health of living beings. Hence, a rapid, sensitive, and selective method for p-NP detection is urgently needed. Herein, for the first time, we successfully synthesized fluorescent carbon dots (CDs) from Bacillus cereus (BC) via a one-step hydrothermal process. The obtained CDs-BC can be applied as a rapid, highly selective, and sensitive sensor for p-NP detection. The fluorescence quenching efficiency of the CD-BC sensor exhibited excellent linear responses with p-NP concentrations at both 0.3-6.5 mu M and 6.5-30 mu M, with a detection limit of 0.11 mu M. The mechanism of p-NP detection is based on the inner filter effect (IFE). Preliminary bacteria, cell, and animal studies showed that the as-prepared CDs-BC possess high photostability, excellent biocompatibility, low or no biotoxicity, and multicolor fluorescence emission properties; furthermore, they can be rapidly excreted from the body of mice, which suggests their potential for applications in the biomedical field.
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