期刊
HELIYON
卷 5, 期 8, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.heliyon.2019.e02192
关键词
Microbiology; Biofilms; Intervention; Treatment; Antibiotic resistance; Quorum sensing
资金
- Mekelle University [AU/003/2018/2029]
- Pan African University, Institute for Basic Sciences, Technology and Innovation, Africa-ai-Japan Project [AU/003/2018/2029]
Background: Biofilms are multicellular communities of microorganisms held together by a self-produced extra cellular matrix. The ability of microbes to form biofilm is a universal, ubiquitous, and dynamic process. This dynamic process of biofilms establishes an important strategy to withstand and survive harsh environmental conditions and antimicrobial agents. Objective: This review paper aims to give an overview of antibiotic resistance, intervention, and treatment of infections caused by biofilm-forming organisms. Moreover, it can also help to motivate scholars to search for new anti-biofilm strategies and most appropriate methods to tackle the effect of biofilm infections on healthcare services. Methods: This paper was written by reviewing recent research and review articles which are reporting about the antibiotic resistance, prevention, and treatment of biofilm-producing organisms. Conclusion: Bioprospecting for quorum quenching compounds can be an appropriate solution for controlling biofilm infections.
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