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The 15q13.3 deletion syndrome: Deficient α7-containing nicotinic acetylcholine receptor-mediated neurotransmission in the pathogenesis of neurodevelopmental disorders
Stephen I. Deutsch et al.
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Javier Egea et al.
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Anna Chatzidaki et al.
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Robert Zdanowski et al.
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Carlos A. Baez-Pagan et al.
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Melissa L. Sinkus et al.
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The nicotinic acetylcholine receptor and its prokaryotic homologues: Structure, conformational transitions & allosteric modulation
Marco Cecchini et al.
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Multiple binding sites in the nicotinic acetylcholine receptors: An opportunity for polypharmacolgy
Patricio Iturriaga-Vasquez et al.
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Nicotinic ACh receptors as therapeutic targets in CNS disorders
Kelly T. Dineley et al.
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Corrie J. B. daCosta et al.
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JasKiran K. Gill-Thind et al.
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Morten Skott Thomsen et al.
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Patricia Moeller-Acuna et al.
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Galyna Gergalova et al.
INTERNATIONAL JOURNAL OF BIOCHEMISTRY & CELL BIOLOGY (2014)
Mode of action of the positive modulator PNU-120596 on α7 nicotinic acetylcholine receptors
Anett K. Szabo et al.
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Kinetic properties and open probability of α7 nicotinic acetylcholine receptors
Krisztina Pesti et al.
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The Novel α7β2-Nicotinic Acetylcholine Receptor Subtype Is Expressed in Mouse and Human Basal Forebrain: Biochemical and Pharmacological Characterization
Milena Moretti et al.
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Esther Parada et al.
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Inter-residue coupling contributes to high-affinity subtype-selective binding of α-bungarotoxin to nicotinic receptors
Steven M. Sine et al.
BIOCHEMICAL JOURNAL (2013)
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Nadine Kabbani et al.
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BRAIN RESEARCH BULLETIN (2013)
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Corrie J. B. daCosta et al.
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Corbett Bennett et al.
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Marie Jindrichova et al.
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Activation of α7 Nicotinic Receptors by Orthosteric and Allosteric Agonists: Influence on Single-Channel Kinetics and Conductance
Magda M. Palczynska et al.
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Dustin K. Williams et al.
BIOCHEMICAL PHARMACOLOGY (2011)
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Hugo R. Arias et al.
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Chih-Hsiung Wu et al.
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Simone Mazzaferro et al.
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JasKiran K. Gill et al.
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Voltage- and temperature-dependent allosteric modulation of alpha 7 nicotinic receptors by PNU120596
Fabrio Sitzia et al.
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Jens Halvard Gronlien et al.
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Rapid desensitization of the rat α7 nAChR is facilitated by the presence of a proline residue in the outer β-sheet
Thomas J. McCormack et al.
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Localization by site-directed mutagenesis of a galantamine binding site on α7 nicotinic acetylcholine receptor extracellular domain
Juergen Ludwig et al.
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Toby Collins et al.
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Single-Channel Kinetic Analysis for Activation and Desensitization of Homomeric 5-HT3A Receptors
Jeremias Corradi et al.
BIOPHYSICAL JOURNAL (2009)
Pentameric concatenated (α4)2(β2)3 and (α4)3(β2)2 nicotinic acetylcholine receptors: subunit arrangement determines functional expression
A-L Carbone et al.
BRITISH JOURNAL OF PHARMACOLOGY (2009)
To channel or not to channel? Functioning of nicotinic acetylcholine receptors in leukocytes
Maryna V. Skok
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Number and Locations of Agonist Binding Sites Required to Activate Homomeric Cys-Loop Receptors
Diego Rayes et al.
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Detection and trapping of intermediate states priming nicotinic receptor channel opening
Nuriya Mukhtasimova et al.
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Acetylcholine beyond neurons: the non-neuronal cholinergic system in humans
I. Wessler et al.
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The interface between extracellular and transmembrane domains of homomeric Cys-loop receptors governs open-channel lifetime and rate of desensitization
Cecilia Bouzat et al.
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Daniel Bertrand et al.
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Remigijus Lape et al.
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Balazs Lendvai et al.
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Gareth T. Young et al.
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WY Lee et al.
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D Rayes et al.
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R Zwart et al.
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Intracellular Ca2+ signals evoked by stimulation of nicotinic acetylcholine receptors in SH-SY5Y cells:: contribution of voltage-operated Ca2+ channels and Ca2+ stores
FA Dajas-Bailador et al.
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S Halevi et al.
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N Le Novere et al.
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A Mike et al.
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