4.2 Article

Hypothesis testing near singularities and boundaries

期刊

ELECTRONIC JOURNAL OF STATISTICS
卷 13, 期 1, 页码 2150-2193

出版社

INST MATHEMATICAL STATISTICS
DOI: 10.1214/19-EJS1576

关键词

Hypothesis testing; singularity; boundary; likelihood ratio statistic; chi-squared; phylogenomics; coalescent

资金

  1. US National Institutes of Health under the Joint DMS/NIGMS Initiative [R01 GM117590]

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The likelihood ratio statistic, with its asymptotic chi(2) distribution at regular model points, is often used for hypothesis testing. However, the asymptotic distribution can differ at model singularities and boundaries, suggesting the use of a chi(2) might be problematic nearby. Indeed, its poor behavior for testing near singularities and boundaries is apparent in simulations, and can lead to conservative or anti-conservative tests. Here we develop a new distribution designed for use in hypothesis testing near singularities and boundaries, which asymptotically agrees with that of the likelihood ratio statistic. For two example trinomial models, arising in the context of inference of evolutionary trees, we show the new distributions outperform a chi(2).

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