期刊
BIOSENSORS-BASEL
卷 9, 期 3, 页码 -出版社
MDPI
DOI: 10.3390/bios9030108
关键词
biosensor; impedance spectroscopy; coplanar electrodes; biological cell detection
资金
- European Regional Development Fund (FEDER)
- program 80' PRIME of the Conseil National de la Recherche Scientifique (CNRS)
- Region Grand Est-France
New technologies, such as biosensors and lab-on-a-chip, are reducing time consumption and costs for the detection and characterization of biological cells. One challenge is to detect and characterize cells and bacteria one by one or at a very low concentration. In this case, measurements have very low variations that can be difficult to detect. In this article, the use of an insulation layer on the connection tracks of a biosensor with coplanar electrodes is proposed to improve a biosensor previously developed. The impedance spectroscopy technique was used to analyze the influence of the insulation layer on the cutoff frequencies and on the normalized impedance variation. This solution does not induce changes in the cutoff frequencies, though it permits improving the normalized impedance variations, compared to the same biosensor without the insulation layer.
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