期刊
CHEMICAL COMMUNICATIONS
卷 55, 期 82, 页码 12308-12311出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc06869d
关键词
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资金
- NSFC/China [21622602, 21788102, 21421004, 21636002, 21878087, 21908060]
- National Key Research and Development Program [2017YFC-0906902]
- Innovation Program of Shanghai Municipal Education Commission
- Scientific Committee of Shanghai [15XD1501400]
- Shuguang Program [18SG27]
- China Postdoctoral Science Foundation [2019M651417]
Herein, we developed a dual-channel and light-up near-infrared fluorescent probe for ratiometric sensing of beta-galactosidase (beta-gal) activity. The well-designed probe, which shows ratiometric optical response with a significant red-shift (from 575 nm to 730 nm), was successfully applied to detect endogenous beta-gal activity in SKOV-3 cells and tumor-bearing mice.
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