期刊
ORGANIC CHEMISTRY FRONTIERS
卷 6, 期 20, 页码 3562-3565出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9qo00842j
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资金
- National Natural Science Foundation of China [21402137]
- Chemical Engineering & Technology of Zhejiang Province First-Class Discipline (Taizhou University)
We have developed a transition metal free method for efficient and chemoselective reduction of C=O bonds using DMF as a hydrogen source and solvent. alpha-Ketoamides bearing various functional groups are smoothly reduced to alpha-hydroxyamides in high yields with the present DMF/NaOH/H2O reduction system.
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