期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 82, 期 7, 页码 3605-3611出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b00129
关键词
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资金
- NSFC [21232004, 21472071, 21602087]
- TAPP of Jiangsu Higher Education Institutions
- PAPD of Jiangsu Higher Education Institutions
- Outstanding Youth Fund of JSNU [YQ2015003]
- NSF of Jiangsu Province [BK20151163, BK20160212]
- NSF of Jiangsu Education Committee [15KJB150006]
A new and highly eco-friendly approach to diverse and functionalized oxazolo[5,4-b]indoles with good yield and high diastereoselectivity (up to >99:1) has been disclosed from simple and readily available arylglyoxals with cyclic enaminones and amino acids. These microwave-assisted transformations in environmentally compatible ethanol resulted in continuous multiple bond-forming events including C-C, C-N, and C-O bonds, enabling catalyst-free multicomponent bicyclizations to rapidly build up functional N,O-heterocycles.
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