期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 82, 期 6, 页码 3302-3310出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b00013
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资金
- CNRS
- University Paris-Est
1,2-Disubstituted indolines have been prepared in fair to good yields by a Zn-mediated organometallic Mannich reaction, followed by an intramolecular Pd-catalyzed aromatic amination. The reactions are easy to set up and compatible with a large variety of simple or commercially available reagents. The method was further extended to the preparation of a 1,2,3-trisubstituted indoline.
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