期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 82, 期 2, 页码 1285-1290出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.6b02950
关键词
-
资金
- NSFC [21602248, 21472236]
- Chinese Universities Scientific Fund
A modified Bouveault Blanc reduction has been developed for the synthesis of alpha,alpha-dideuterio alcohols from carboxylic acid esters. Sodium dispersions are used as the electron donor in this electron transfer reaction, and ethanol -d(1), is employed as the deuterium source. This reaction uses stable, a a cheap, and commercially available reagents, is operationally simple, and results in excellent deuterium incorporation across a broad range of aliphatic esters, which provides an attractive, alternative to reactions mediated by expensive pyrophoric alkali metal deuterides.
作者
我是这篇论文的作者
点击您的名字以认领此论文并将其添加到您的个人资料中。
推荐
暂无数据