期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 82, 期 23, 页码 12141-12152出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b01855
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资金
- National Institute for Medical Research Development (NIMAD)
A diversity-oriented access to diastereoselective arylidene 2,5-diketopiperazines is elaborated via a sequential Ugi post-transformation involving catalytic cyclization and oxidative Heck reaction sequence. This sequence offers an interesting multicomponent entry to a library of 2,5-diketopiperazines and arylidene 2,5-diketopiperazines under mild reaction conditions in good to excellent yields.
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