期刊
JOURNAL OF ORGANIC CHEMISTRY
卷 82, 期 11, 页码 5940-5946出版社
AMER CHEMICAL SOC
DOI: 10.1021/acs.joc.7b00439
关键词
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资金
- CSIR, New Delhi [21 (2003)/16/EMR II]
- CSIR, New Delhi, India for senior research fellowship
A one step formal [3+2]-annulation protocol for the synthesis of 2,3-disubstituted indolines is described. The in situ generated aryne acts as a two-atom component, and gamma-amino-alpha,beta-unsaturated esters acting as a three-atom component to construct indoline units in a highly regio- and diastereoselective manner with yields ranging from 63 to 80%.
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