4.6 Article

Extended-arch repair for acute type-A aortic dissection: perioperative and mid-term results

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EUROPEAN JOURNAL OF CARDIO-THORACIC SURGERY
卷 56, 期 4, 页码 714-721

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OXFORD UNIV PRESS INC
DOI: 10.1093/ejcts/ezz071

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Type-A aortic dissection; Extended-arch; Hemiarch; Hybrid arch; Endovascular

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OBJECTIVES: Extended-arch techniques offer the potential to comprehensively treat acute type-A aortic dissection (ATAAD), but add surgical complexity compared to the standard hemiarch technique. This study describes both perioperative and mid-term outcomes following the introduction of an extended-arch technique for ATAAD. METHODS: Ours is a retrospective single-centre observational study of 95 consecutive patients with ATAAD from 2011 to 2016. The decision to perform extended-arch or hemiarch repair was individualized based on clinical and radiological features. Extended-arch repair was defined as replacement of the ascending aorta and arch with reimplantation of head vessels with or without distal endovascular extension. Clinical follow-up was 100% complete. Cross-sectional double-oblique measurements were performed for aortic remodelling analysis. RESULTS: Extended-arch (n=28) and hemiarch (n=67) repair resulted in a in-hospital mortality of 10% (n=3) and 10%, (n=7), and permanent neurological deficit rate of 7% and 12%, respectively. At a mean imaging follow-up duration of 2.71.5 years, false lumen thrombosis was achieved in 57% and 9% of patients undergoing extended-arch and hemiarch repair, respectively. Rate of growth in the proximal descending aorta was 0.7 +/- 2.3 mm/year in the extended-arch group vs 2.7 +/- 3.9 mm/year in the hemiarch group. At a mean clinical follow-up time of 3.0 +/- 1.6 years, open surgical aortic reoperation was 0% in the extended-arch group and 22% in the hemiarch group. CONCLUSIONS: Extended-arch repair of ATAAD can be introduced in the acute setting without increase in perioperative mortality or morbidity. At mid-term follow-up, extended-arch for ATAAD improves aortic remodelling and reduces the need for open surgical reoperation.

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