期刊
JOURNAL OF NEUROSURGERY-PEDIATRICS
卷 20, 期 1, 页码 51-55出版社
AMER ASSOC NEUROLOGICAL SURGEONS
DOI: 10.3171/2017.2.PEDS16679
关键词
GOPC; ROSI; receptor protein-tyrosine kinases; 6q22 deletion; oncology
Pediatric high-grade glioma is a rare tumor characterized by high mortality. The authors report the first case of a high-grade glioma associated with aGOPC(FIG)-ROSI fusion in a pediatric patient. The patient underwent gross-total resection at the age of 4 years, followed by adjuvant high-dose chemotherapy and autologous hematopoietic stem cell rescue. At 30 months after transplantation, she remains disease free.
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