Identification and characterization of genetic structures coding for carbapenemases in enterobacteria from Central Greece

The dissemination of carbapenemases among different species of Enterobacteriaceae was investigated in the University Hospital of Larissa, Central Greece. The presence of the isoform (Tn4401a) of the transponson carrying bla(KPC-2) and 5 divergent bla(VIM)-carrying class I integrons, including a novel structure, suggests interspecies transfer of these mobile elements and underscores their ongoing evolution. (C) 2015 Elsevier Inc. All rights reserved.