期刊
HELIYON
卷 5, 期 10, 页码 -出版社
ELSEVIER SCI LTD
DOI: 10.1016/j.heliyon.2019.e02607
关键词
Inorganic chemistry; Organic chemistry; Bacteria; Microorganism; Biofilms; Antibacterial activity; Imidazolium salt; Ionic liquids; Imidazolium cation; Antibiofilm effect
资金
- Ege University, Scientific Research Project (BAP) [16FBE008]
A series of imidazolium bromide salts (NIM-Br 1a, 1b and 1c) bearing different lengths of alkyl chains were synthesized and theirin vitro antibacterial activities were determined by measuring the minimum inhibitory concentration (MIC) values for Staphylococcus aureus, Escherichia coli, Pseudomonas aeruginosa and Enterococcus faecalis. In addition, these imidazolium derivatives were also evaluated against biofilm produced by these bacterial strains. All compounds were found to be effective against Gram-positive and Gram-negative bacteria, and also more effective on the S. aureus biofilm production than the others.
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