期刊
CHEMICAL COMMUNICATIONS
卷 55, 期 90, 页码 13526-13529出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9cc06937b
关键词
-
资金
- Science Foundation Ireland
- Solid State Pharmaceutical Centre [12/RC/2275]
A new strategy for the protection of amines has been developed involving reaction with pyridil under the influence of N-heterocyclic carbene catalysis. The methodology is capable of distinguishing between two amines characterised by small differences in steric bulk and the resulting pyridoyl amides can be cleaved without requiring either strongly acidic or basic hydrolysis.
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