期刊
JOURNAL OF MOLECULAR LIQUIDS
卷 230, 期 -, 页码 705-713出版社
ELSEVIER
DOI: 10.1016/j.molliq.2017.01.004
关键词
AgNPs; Jatropha curcas; Lannea grandis; Candida albicans; Antifungal; Plant latex
We report a completely green, cheap and convenient route for the fabrication of highly stable silver nanocolloid from aqueous silver nitrate using latex of two different plantJatropha curcas and Lannea grandis. The existence of silver nanoparticle has been proved by UV Vis spectroscopy, electron diffraction and energy dispersive X-ray (EDX) analysis. The transmission electron microscopy (TEM) images show relatively higher polydispersity with average diameter 47.0 +/- 2.0 nm of nanoparticle synthesized by latex of J. curcas where as latex of L. grandis generated highly monodisperse spherical particle having average diameter 7.6 +/- 0.5 nm. The Fourier transform infrared (FTIR) spectra and HRTEM image demonstrate that the components of latex interacted with the surface of silver nanoparticle to make a thin layer of coating on the metal. The as-synthesized silver nanocolloid is a highly stable dispersion which exhibited no precipitation even after one year of storage. The cyto-toxicity of the nanocolloid has been tested out by hemolytic study of goat red blood corpuscles. Furthermore, we also tested the antifungal activity of this low-cytotoxic silver nanocolloid against plankotonic cell as well as biofilm of Candida albicans by spectrophotometric and microscopic (light microscopy and scanning electron microscopy) analysis. Our finding demonstrates that the bio-fabricated silver nanocolloid can be used as promising nano-drug formulation to combat against fungal infections. (C) 2017 Elsevier B.V. All rights reserved.
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