期刊
CURRENT NUTRITION REPORTS
卷 8, 期 4, 页码 307-316出版社
SPRINGERNATURE
DOI: 10.1007/s13668-019-00281-5
关键词
Obesity; Gut microbiota; Polyphenols; Dietary fibers; Prebiotics
资金
- FNRS, FRFS-WELBIO [WELBIO-CR-2017-C02]
- The Excellence Of Science [EOS 30770923]
- Funds Baillet Latour (Grant for Medical Research 2015)
Purpose of Review In this review, we focus on microbiota modulation using non-digestible carbohydrate and polyphenols (i.e., prebiotics) that have the potential to modulate body weight. Recent Findings Prebiotics derived from plants have gained the interest of public and scientific communities as they may prevent diseases and help maintain health. Summary Maintaining a healthy body weight is key to reducing the risk of developing chronic metabolic complications. However, the prevalence of obesity has increased to pandemic proportions and is now ranked globally in the top five risk factors for death. While diet and behavioral modification programs aiming to reduce weight gain and promote weight loss are effective in the short term, they remain insufficient over the long haul as compliance is often low and weight regain is very common. As a result, novel dietary strategies targeting the gut microbiota have been successful in decreasing obesity and metabolic disorders via different molecular mechanisms.
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