期刊
JOURNAL OF MINIMALLY INVASIVE GYNECOLOGY
卷 24, 期 1, 页码 98-102出版社
ELSEVIER SCIENCE INC
DOI: 10.1016/j.jmig.2016.09.018
关键词
Laparoscopy; Long-term outcomes; Open surgery; Ovarian cancer; Survival
Study Objective: Growing evidence supports the safety of a laparoscopic approach for patients affected by apparent early stage ovarian cancer. However, no well-designed studies comparing laparoscopic and open surgical staging are available. In the present investigation we aimed to provide a balanced long-term comparison between these 2 approaches. Design: Retrospective study (Canadian Task Force classification II-2). Setting: Tertiary center. Patients: Data of consecutive patients affected by early-stage ovarian cancer who had laparoscopic staging were matched 1:1 with a cohort of patients undergoing open surgical staging. The matching was conducted by a propensity-score comparison. Intervention: Laparoscopic and open surgical staging. Measurements and Main Results: Fifty patient pairs (100 patients: 50 undergoing laparoscopic staging vs 50 undergoing open surgical staging) were included. Demographic and baseline oncologic characteristics were balanced between groups (p > .2). We observed that patients undergoing laparoscopic staging experienced longer operative time (207.2 [71.6] minutes vs 180.7 [47.0] minutes; p = .04), lower blood loss (150 [52.7] mL vs 339.8 [225.9] mL; p < .001), and shorter length of hospital stay (4.0 [2.6] days vs 6.1 [1.6] days; p < .001) compared with patients undergoing open surgical staging. No conversion to open surgery occurred. Complication rate was similar between groups. No difference in survival outcomes were observed, after a mean (SD) follow-up of 49.5 (64) and 52.6 (31.7) months after laparoscopic and open surgical staging, respectively. Conclusions: Our findings suggest that the implementation of minimally invasive staging does not influence survival outcomes of patients affected by early-stage ovarian cancer. Laparoscopic staging improved patient outcomes, reducing length of hospital stay. Further large prospective studies are warranted. (C) 2016 AAGL. All rights reserved.
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