期刊
JOURNAL OF MICROBIOLOGICAL METHODS
卷 139, 期 -, 页码 165-167出版社
ELSEVIER SCIENCE BV
DOI: 10.1016/j.mimet.2017.06.001
关键词
Mycobacterium tuberculosis; Fluorescence Resonance Energy Transfer; Gold nanoparticles; 16s rDNA; In vitro diagnosis
资金
- NPRP award from the Qatar National Research Fund (Qatar Foundation) [NPRP 4-1215-3-317]
The global combat against MTB is limited by challenges in accurate affordable detection. In this study, a rapid, affordable, single tube system for detection of unamplified MTB16s rDNA was developed. Utilizing a AuNP based FRET system, this assay achieved a sensitivity and specificity of 98.6% and 90% respectively.
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