期刊
MEDCHEMCOMM
卷 10, 期 11, 页码 1867-1870出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9md00233b
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资金
- AiCuris Anti-Infective Cures GmbH, Germany
Pritelivir (AIC316, BAY 57-1293) was discovered as a highly potent drug against herpes simplex viruses with a novel mode of action, i.e. inhibition of the viral helicase-primase. A side by side comparison of the oral form against Valtrex (TM) in patients with genital herpes, showed superiority in phase II testing for Pritelivir. A number of different solid forms have been generated for additional, e.g. systemic, or topical applications.
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