4.7 Article

Fragment-to-Lead Medicinal Chemistry Publications in 2016

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JOURNAL OF MEDICINAL CHEMISTRY
卷 61, 期 5, 页码 1774-1784

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AMER CHEMICAL SOC
DOI: 10.1021/acs.jmedchem.7b01298

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The popularity of fragment-based drug discovery (FBDD) is demonstrated by the number of recent successful fragment-to-lead (F2L) publications. This Miniperspective provides a tabulated summary of the F2L literature published in the year 2016, along with discussion of general trends. It uses the same format as our summary of the 2015 literature and is intended to be a resource for both FBDD practitioners and medicinal chemists in general.

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