期刊
JOURNAL OF MATERIALS CHEMISTRY B
卷 7, 期 45, 页码 7075-7089出版社
ROYAL SOC CHEMISTRY
DOI: 10.1039/c9tb01730e
关键词
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资金
- National Science and Technology Major Project of the Ministry of Science and Technology of China [2018ZX10301402]
- International Cooperation and Exchange of the National Natural Science Foundation of China [51820105004]
- Science and Technology Program of Guangzhou [201707010094]
- Guangdong Innovative and Entrepreneurial Research Team Program [2013S086, 2016ZT06S029]
- Science and Technology Planning Project of Shenzhen [JCYJ20170307141438157]
- Fundamental Research Funds for the Central Universities [19lgpy209]
The discovery of novel methods to fabricate optimal scaffolds that mimic both mechanical and functional properties of the extracellular matrix (ECM) has always been the holy grail in tissue engineering. In recent years, electrospinning has emerged as an attractive material fabrication method and has been widely applied in tissue engineering due to its capability of producing non-woven and nanoscale fibers. However, from the perspective of biomimicry, it is difficult for single-component electrospun fiber membranes to achieve the biomimetic purposes of the multi-component extracellular matrix. Based on electrospinning, various functional components can be efficiently and expediently introduced into the membranes, and through the complementation and correlation of the properties of each component, composite materials with comprehensive and superior properties are obtained while maintaining the primitive merits of each component. In this review, we will provide an overview of the attempts made to fabricate electrospinning-based composite tissue engineering materials in the past few decades, which have been divided into organic additives, inorganic additives and organic-inorganic additives.
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