期刊
CLINICAL AND TRANSLATIONAL RADIATION ONCOLOGY
卷 19, 期 -, 页码 27-32出版社
ELSEVIER IRELAND LTD
DOI: 10.1016/j.ctro.2019.07.006
关键词
IGRT; Adaptive; Bladder; Radiotherapy; Trial QA
资金
- Cancer Research UK [CRUK/12/055]
- Cancer Research UK (CRUK) core grant [C1491/A15955]
Background and purpose: Hypofractionated bladder RT with or without image guided adaptive planning (HYBRID) is a multicentre clinical trial investigating Plan of the Day (PoD) adaptive radiotherapy for bladder cancer. To ensure correct PoD selection a pre-accrual guidance and assessment module was developed as part of an image guided radiotherapy quality assurance (IGRT QA) credentialing programme. This study aimed to evaluate its feasibility and effectiveness across multiple recruiting centres. Materials and methods: Individuals from participating centres remotely accessed an image database in order to complete the PoD module. An assessment score of >= 83% was required in order to receive QA approval. A questionnaire was used to gather user feedback on the module. PoD decisions for the first patient at each recruiting centre were retrospectively reviewed for protocol adherence. Results: 71 radiation therapists (RTTs) from 10 centres completed the PoD module. The median assessment score was 92% (Range: 58-100%) with 79% of RTTs passing the assessment on first attempt. All questionnaire respondents reported that the PoD module prepared them for plan selection. In 51/60 of on-trial treatments reviewed, the PoD selected by the centre agreed with QA reviewers. Conclusions: The PoD QA module was successfully implemented in a multicentre trial and enabled pre-accrual assessment of protocol understanding. This increased operator confidence and resulted in appropriate PoD selection on-trial. Crown Copyright (C) 2019 Published by Elsevier B.V. on behalf of European Society for Radiotherapy and Oncology.
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